Mitra A, Goldstein R Y
Section of Plastic and Reconstructive Surgery, Temple University Hospital School of Medicine, Philadelphia, PA 19140.
Ann Plast Surg. 1994 Jun;32(6):619-22. doi: 10.1097/00000637-199406000-00010.
There is general agreement that Dupuytren's contracture is a genetic disorder that occurs predominantly in white men of Northern European ancestry. It appears rarely in the purely black population. We present our experience from Temple University of 8 black patients with Dupuytren's contracture. We also present a review of the world literature dealing with the black population and Dupuytren's disease. A total of 23 patients are reviewed, including our group. They all fall into the category of no Caucasian admixture and negative family history of Dupuytren's contracture. Every patient reviewed has at least 1 hand involved. History and presentation of disease, as well as epidemiological associations (e.g., age distribution, diabetes, and epilepsy), in our review are similar to that seen in the Caucasian population. The diathesis or predisposition for Dupuytren's contracture appears to be less extensive in our series of 8 black patients. History taking, with regard to occupation and possible traumatic etiology, remains a very useful tool.
普遍认为，杜普伊特伦挛缩症是一种遗传性疾病，主要发生在北欧血统的白人男性中。在纯黑人种群中很少出现。我们介绍了坦普尔大学8例患有杜普伊特伦挛缩症黑人患者的情况。我们还对世界范围内有关黑人种群与杜普伊特伦病的文献进行了综述。包括我们的病例组在内，共对23例患者进行了综述。他们均属于无白种人混血且杜普伊特伦挛缩症家族史为阴性的类别。每例接受综述的患者至少有1只手受累。在我们的综述中，疾病的病史和表现以及流行病学关联（如年龄分布、糖尿病和癫痫）与白种人种群中所见相似。在我们这组8例黑人患者中，杜普伊特伦挛缩症的素质或易感性似乎没那么广泛。关于职业和可能的创伤病因的病史采集仍然是一项非常有用的工具。
