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[医源性呼吸道狭窄。治疗指征的演变。基于217例手术病例]

[Iatrogenic stenoses of the respiratory tract. Evolution of therapeutic indications. Based on 217 surgical cases].

作者信息

Couraud L, Jougon J, Velly J F, Klein C

机构信息

Service de Chirurgie Thoracique, Université de Bordeaux, Hôpital Xavier Arnozan, Pessac.

出版信息

Ann Chir. 1994;48(3):277-83.

PMID:8074414
Abstract

The authors report a series of 217 non-neoplastic stenoses of the upper airways operated in the period 1978-1991. One hundred and twenty patients with tracheal stenoses underwent tracheal resection and end-to-end anastomosis, with 117 excellent results and 3 deaths. The treatment of 97 patients with laryngotracheal stenoses was much more complex and difficult to manage: Fifty-nine underwent tracheal and subglottic resection-anastomosis with 58 successes and 1 death--Seven had resection-anastomosis with total cricoidectomy and stenting. They were 6 successes and 1 death--Three had supraglottic resection-anastomosis with 3 successes--Twelve underwent laryngeal enlargement over a T-tube with successes in 11 cases and failure in 1 case. Sixteen had complex combinations of resection and modeling with 13 successes, 2 failures, and 1 death. In this series under the same therapeutic options, the results were successful in 96% of cases, with 4% of failures (7% of them resulting in death). The anatomical type, tracheal or laryngotracheal, length of the stenosis, neuropsychological sequelae, and overall poor respiratory status of the patients must be taken into account before deciding the therapeutic strategy. Old age is not a contraindication to tracheal resection, but is certainly a risk factor for morbidity and mortality. The key to success is undoubtedly careful preoperative preparation, treatment of local infection and inflammation, as well as meticulous mucomucosal approximation of healthy margins at the anastomosis.

摘要

作者报告了1978年至1991年期间接受手术治疗的217例上气道非肿瘤性狭窄病例。120例气管狭窄患者接受了气管切除及端端吻合术,其中117例效果良好,3例死亡。97例喉气管狭窄患者的治疗则复杂得多且难以处理:59例行气管及声门下切除吻合术,58例成功,1例死亡;7例行环状软骨全切除及支架置入的切除吻合术,6例成功,1例死亡;3例行声门上切除吻合术,3例成功;12例行T形管置入下的喉扩大术,11例成功,1例失败;16例行复杂的切除与塑形联合手术,13例成功,2例失败,1例死亡。在本系列病例中,采用相同的治疗方案,96%的病例治疗成功,4%失败(其中7%导致死亡)。在决定治疗策略之前,必须考虑解剖类型(气管型或喉气管型)、狭窄长度、神经心理后遗症以及患者整体呼吸状况较差等因素。高龄并非气管切除的禁忌证,但无疑是发病和死亡的危险因素。成功的关键无疑是术前精心准备、局部感染和炎症的治疗,以及吻合时健康边缘的细致黏膜对合。

相似文献

1
[Iatrogenic stenoses of the respiratory tract. Evolution of therapeutic indications. Based on 217 surgical cases].[医源性呼吸道狭窄。治疗指征的演变。基于217例手术病例]
Ann Chir. 1994;48(3):277-83.
2
Surgical treatment of nontumoral stenoses of the upper airway.上气道非肿瘤性狭窄的外科治疗。
Ann Thorac Surg. 1995 Aug;60(2):250-9; discussion 259-60. doi: 10.1016/0003-4975(95)00464-v.
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Tracheal sleeve resection for iatrogenic stenoses (subglottic laryngeal and tracheal).医源性狭窄(声门下喉和气管)的气管袖状切除术
J Thorac Cardiovasc Surg. 1992 Oct;104(4):882-7.
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[Therapeutic approach and results in the treatment of subglottic tracheal stenosis].[声门下气管狭窄的治疗方法及治疗结果]
Med Pregl. 2000 Jul-Aug;53(7-8):349-53.
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[Laryngeal and tracheal stenoses after intubation and/or tracheotomy. A review of 32 cases including 39 lesions and 33 operations (author's transl)].[插管和/或气管切开术后的喉气管狭窄。32例病例回顾,包括39处病变和33次手术(作者译)]
Acta Chir Belg. 1977 May-Jun;76(3):381-5.
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[Tracheal resection-anastomosis for iatrogenic stenosis. Experience in 340 cases].[医源性气管狭窄的气管切除吻合术。340例经验]
Rev Mal Respir. 1998 Oct;15(5):627-32.
7
Management of postintubation tracheal stenosis: appropriate indications make outcome differences.经气管插管后气管狭窄的管理:合适的适应证可使结果产生差异。
Respiration. 2010;79(5):395-401. doi: 10.1159/000279225. Epub 2010 Jan 26.
8
Subglottic tracheal resection and synchronous laryngeal reconstruction.声门下气管切除术及同期喉重建术
J Thorac Cardiovasc Surg. 1992 Nov;104(5):1443-50.
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Tracheal resection with end-to-end anastomosis for post-intubation cervical tracheal stenosis: study of 14 cases.气管端端吻合术治疗气管插管后颈段气管狭窄:14例研究
J Laryngol Otol. 2011 Sep;125(9):958-61. doi: 10.1017/S002221511100137X. Epub 2011 Jun 7.
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[Efficacy of bronchoscopic Nd:YAG laser therapy for laryngotracheal stenoses after long-term intubation].[支气管镜下钕钇铝石榴石激光治疗长期插管后喉气管狭窄的疗效]
Chirurg. 1996 Jul;67(7):730-3.

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Surgical management of laryngotracheal stenosis in adults.成人喉气管狭窄的外科治疗
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