造血祖细胞基因转移的现状：在朗格汉斯细胞组织细胞增多症中的应用
Current status of gene transfer into haemopoietic progenitor cells: application to Langerhans cell histiocytosis.
作者信息
Brenner M
机构信息
Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105.
出版信息
Br J Cancer Suppl. 1994 Sep;23:S56-7.
Abstract
A number of recent studies have shown that it is possible to obtain significant levels of gene transfer and expression in marrow progenitor cells and their progeny by using retroviral vectors. The data obtained from these studies and the possible applications to Langerhans cell histiocytosis (LCH) are reviewed.
摘要
最近的一些研究表明，通过使用逆转录病毒载体，有可能在骨髓祖细胞及其后代中获得显著水平的基因转移和表达。本文综述了这些研究获得的数据以及其在朗格汉斯细胞组织细胞增多症（LCH）中的可能应用。
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