Brenner M
Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105.
Br J Cancer Suppl. 1994 Sep;23:S56-7.
A number of recent studies have shown that it is possible to obtain significant levels of gene transfer and expression in marrow progenitor cells and their progeny by using retroviral vectors. The data obtained from these studies and the possible applications to Langerhans cell histiocytosis (LCH) are reviewed.