Abrahamsen A F, Lien H H, Aas M, Winderen M, Hager B, Kvaløy S, Elgjo R F, Nome O
Department of Medical Oncology and Radiotherapy, Norwegian Radium Hospital, Oslo.
Ann Oncol. 1994 May;5(5):433-6. doi: 10.1093/oxfordjournals.annonc.a058875.
A residual mediastinal mass is common after treatment for bulky mediastinal lymphoma and represents a difficult diagnostic problem.
19 patients with bulky mediastinal masses due to malignant lymphoma had computed tomography (CT), magnetic resonance imaging (MRI) and 67Gallium scan (67Ga) before treatment, after four cycles of chemotherapy, and two, six and twelve months after end of treatment.
MRI and 67Ga showed active tumor in all patients before treatment. Twelve months after treatment full consistency was found between the results of the two techniques. During treatment and the first six months after treatment, the two techniques were not in accord in some patients, partly due to later normalization of MRI compared with 67Ga.
Both MRI and 67Ga are useful in assessing tumor activity in lymphoma mediastinal masses.
巨大纵隔淋巴瘤治疗后残留纵隔肿块很常见,这是一个诊断难题。
19例因恶性淋巴瘤导致巨大纵隔肿块的患者在治疗前、化疗四个周期后以及治疗结束后两个月、六个月和十二个月接受了计算机断层扫描(CT)、磁共振成像(MRI)和67镓扫描(67Ga)。
治疗前MRI和67Ga显示所有患者均有活性肿瘤。治疗十二个月后,两种技术的结果完全一致。在治疗期间和治疗后的前六个月,部分患者的两种技术结果不一致,部分原因是MRI较67Ga归一化时间更晚。
MRI和67Ga在评估淋巴瘤纵隔肿块的肿瘤活性方面均有用。