Lengerich E J, Addiss D G, Juranek D D
Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.
Clin Infect Dis. 1994 May;18(5):760-3. doi: 10.1093/clinids/18.5.760.
Giardia lamblia is a common gastrointestinal pathogen but is not generally appreciated as a cause of severe illness. To describe the epidemiology of severe giardiasis, we reviewed data on hospital discharges from the United States and the state of Michigan and compared results for giardiasis with those for shigellosis. From 1979 to 1988, an estimated 4,600 persons were hospitalized for giardiasis annually in the United States; the incidence of giardiasis was 2.0 hospitalizations per 100,000 persons, compared with 2.4 hospitalizations per 100,000 persons for shigellosis. Rates of giardiasis were highest among children younger than 5 years old and women of childbearing age; the median length of hospital stay was 4 days (annual total, 23,238 days). Among residents of Michigan from 1983 to 1987, the average annual incidence of hospitalization was 1.4 per 100,000 persons for giardiasis, compared with 1.0 per 100,000 persons for shigellosis. Volume depletion was the most frequently listed codiagnosis (33.2%); 18.7% of children younger than 5 years old who had severe giardiasis had failure to thrive. Physicians should consider the diagnosis of giardiasis for persons with severe gastrointestinal illness.
蓝氏贾第鞭毛虫是一种常见的胃肠道病原体，但一般不被认为是导致严重疾病的原因。为了描述严重贾第虫病的流行病学特征，我们回顾了美国和密歇根州的医院出院数据，并将贾第虫病的结果与志贺菌病的结果进行了比较。1979年至1988年期间，美国每年估计有4600人因贾第虫病住院；贾第虫病的发病率为每10万人中有2.0例住院，而志贺菌病为每10万人中有2.4例住院。贾第虫病发病率在5岁以下儿童和育龄妇女中最高；住院中位时长为4天（每年总计23238天）。1983年至1987年密歇根州居民中，贾第虫病的年平均住院发病率为每10万人中有1.4例，而志贺菌病为每10万人中有1.0例。容量耗竭是最常列出的共诊断疾病（33.2%）；患有严重贾第虫病的5岁以下儿童中有18.7%发育不良。医生应对患有严重胃肠道疾病的患者考虑贾第虫病的诊断。
