Stals H, Vercammen C, Peeters C, Morren M A
Department of Dermatology, University Hospital, Leuven, Belgium.
Dermatology. 1994;189(2):203-6. doi: 10.1159/000246834.
Drug-induced acanthosis nigricans has been reported in the literature. We present a patient with familial combined hyperlipidemia who developed nicotinic-acid-induced acanthosis nigricans. The literature on the cutaneous side effects of nicotinic acid as well as on the medications that can cause acanthosis nigricans is reviewed. Some hypotheses on the pathogenesis of nicotinic-acid-induced acanthosis are presented.
文献中已有药物性黑棘皮病的报道。我们报告了1例家族性混合型高脂血症患者，该患者发生了烟酸诱导的黑棘皮病。本文对烟酸的皮肤副作用以及可导致黑棘皮病的药物相关文献进行了综述。并提出了一些关于烟酸诱导黑棘皮病发病机制的假说。
