Peña Irún A
Medicina de Familia y Comunitaria, Centro de Salud Sardinero, Santander, Cantabria, España.
Semergen. 2014 May-Jun;40(4):e77-9. doi: 10.1016/j.semerg.2013.03.008. Epub 2013 Jun 6.
Acanthosis nigricans is a skin lesion characterized by the presence of a hyperpigmented, velvety cutaneous thickening that usually appears in flexural areas. Less frequently, it can occur in other locations, such as the dorsum of hands and feet. In this case it is called acral acanthosis nigricans. It is a dermatological manifestation of systemic disease. It is often associated with insulin resistance-mediated endocrine diseases. A case is presented on a patient with acanthosis nigricans secondary to the use of growth hormone.
黑棘皮病是一种皮肤病变,其特征为出现色素沉着过度、天鹅绒样的皮肤增厚,通常出现在皮肤褶皱处。较少见的情况下,它也可发生于其他部位,如手足背部。这种情况被称为肢端黑棘皮病。它是系统性疾病的一种皮肤表现。它常与胰岛素抵抗介导的内分泌疾病相关。本文报道一例因使用生长激素继发黑棘皮病的患者。