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Astrocytoma with a unique telomere association.

作者信息

Harrison K J, Neumann E, Kalousek D K, Norman M G, Masui S, Harrison K

机构信息

Cytogenetics/Embryopathology Laboratory, British Columbia Children's Hospital, Vancouver.

出版信息

Cancer Genet Cytogenet. 1994 Aug;76(1):33-5. doi: 10.1016/0165-4608(94)90066-3.

DOI:10.1016/0165-4608(94)90066-3
PMID:8076347
Abstract

Many primary pediatric brain tumors are characterized by nonrandom cytogenetic abnormalities involving specific structural rearrangements and loss or gain of specific chromosomes. We describe a low-grade cerebellar astrocytoma with telomeric association of chromosomes 18 and 21 in a 7-year old girl. The nonrandom telomeric association of these chromosomes represents a unique cytogenetic finding in this type of pediatric brain tumor.

摘要

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