Schwarz J A, Kaboth U, Reikowski H, Jost H, Müting D, Ortmanns H
Klin Wochenschr. 1975 Jun 1;53(11):535-8. doi: 10.1007/BF01468759.
Monomeric IgM could be found rather frequently in acute hepatitis and chronic aggressive hepatitis and occasionally also in chronic persistent hepatitis. Earlier it was reported in lympho-proliferative-, autoimmune diseases, some infectious diseases and in cirrhosis of the liver. The occurence of monomeric IgM in chronic aggressive hepatitis correlates with the detection of several autoantibodies (ANA, SMA, RF). The 7S-IgM-test may be used as an easily measurable additional criterium for diagnosis and course of chronic liver diseases.
单体IgM在急性肝炎和慢性活动性肝炎中较为常见，在慢性持续性肝炎中偶尔也可发现。此前在淋巴增殖性疾病、自身免疫性疾病、一些传染病及肝硬化中也有相关报道。慢性活动性肝炎中单体IgM的出现与多种自身抗体（抗核抗体、平滑肌抗体、类风湿因子）的检测相关。7S-IgM检测可作为一种易于测量的额外标准，用于诊断和监测慢性肝病的病程。
