Midthjell K, Holmen J, Bjørndal A
National Institute for Public Health, Community Medicine Research Unit, Verdal, Norway.
J Intern Med. 1994 Sep;236(3):255-61. doi: 10.1111/j.1365-2796.1994.tb00793.x.
To describe types of diabetes treatment in a total, adult population, including those on no antidiabetic medication, and to evaluate use of the defined daily doses in estimation of diabetes prevalence.
Cross-sectional epidemiologic survey applying patient-based questionnaires and clinical examinations approaching all inhabitants of > or = 20 years (85,100).
Nord-Trøndelag county in the middle part of Norway.
All known diabetic patients in the county (2242) amongst all participants of > or = 20 years (76,855), registered in 1984-86.
Questionnaire data on type of diabetes treatment including drug doses, measurement of height and weight.
Distribution of types of treatment and of mean drug doses.
Of the diabetic patients of > or = 20 years of age, 20% used insulin, 39% oral hypoglycaemic agents and 41% no antidiabetic medication. Corresponding prevalence figures were 0.6%, 1.1% and 1.2%. Mean daily insulin dose per kg body weight was significantly higher in women than in men. Women with no antidiabetic medication stated a more restricted diet than men. The mean prescribed insulin dose was 14% higher than the defined daily dose, but the corresponding oral agent dose was lower than the defined daily dose.
Sales figures is a bad estimate of total diabetes prevalence due to the high proportion of diabetic patients using no antidiabetic medication. Correction is also necessary when the defined daily dose system is used to estimate the prevalence of medically treated diabetes.
描述成年总体人群中的糖尿病治疗类型，包括未使用抗糖尿病药物的人群，并评估限定日剂量在估计糖尿病患病率中的应用。
采用基于患者的问卷调查和临床检查的横断面流行病学调查，对象为所有年龄≥20岁的居民（85,100人）。
挪威中部的北特伦德拉格郡。
1984 - 1986年登记的所有年龄≥20岁的参与者（76,855人）中的该县所有已知糖尿病患者（2242人）。
关于糖尿病治疗类型的问卷数据，包括药物剂量、身高和体重测量。
治疗类型分布和平均药物剂量。
在年龄≥20岁的糖尿病患者中，20%使用胰岛素，39%使用口服降糖药，41%未使用抗糖尿病药物。相应的患病率分别为0.6%、1.1%和1.2%。女性每千克体重的每日平均胰岛素剂量显著高于男性。未使用抗糖尿病药物的女性表示饮食比男性更受限。规定的平均胰岛素剂量比限定日剂量高14%，但相应的口服药物剂量低于限定日剂量。
由于未使用抗糖尿病药物的糖尿病患者比例较高，药品销售数字对糖尿病总患病率的估计不佳。在使用限定日剂量系统估计药物治疗的糖尿病患病率时也需要进行校正。
