Midthjell K, Holmen J, Bjørndal A, Lund-Larsen G
National Institute for Public Health, Community Medicine Research Centre, Verdal, Norway.
J Epidemiol Community Health. 1992 Oct;46(5):537-42. doi: 10.1136/jech.46.5.537.
The aim was to validate information about diabetes mellitus collected by questionnaire in a large epidemiological survey.
Questions on diabetes diagnosis, medical treatment for diabetes, diabetes duration, and hypertension treatment were selected from the Nord-Trøndelag health survey questionnaires. One of the municipalities was selected for the validation study.
The health survey 1984-86 addressed all inhabitants > or = 20 years of age in Nord-Trøndelag county, Norway; 76,885 (90.3%) of the eligible population participated in answering the question on diabetes.
All inhabitants in the municipality answering "yes" to the question on diabetes (n = 169) and the persons with the same sex born closest before and after each diabetic patient and answering "no" to the diabetes question (n = 338) were included.
A very thorough search was made in the medical files of the general practitioners in the municipality for corresponding information. Compared to the files, diabetes was verified in 163 out of the 169. The commonest cause of discrepancy was renal glycosuria. One out of the 338 registered non-diabetic persons was found to have diabetes. Diabetic patients tended to overestimate diabetes duration significantly. Insulin treatment was verified in 19/20 (95%) and treatment with oral hypoglycaemic agents in all 44 with an affirmative questionnaire answer. A negative answer on insulin and oral hypoglycaemic agents was verified in 100% and 99% respectively.
The concordance was considerably higher than in a comparable Norwegian study performed 10 years earlier. Patient administered questionnaires may be a very reliable source of information for epidemiological purposes in a well defined chronic disease such as diabetes mellitus.
旨在验证在一项大型流行病学调查中通过问卷收集的糖尿病相关信息。
从北特伦德拉格健康调查问卷中选取有关糖尿病诊断、糖尿病治疗、糖尿病病程及高血压治疗的问题。选择其中一个自治市进行验证研究。
1984 - 1986年的健康调查针对挪威北特伦德拉格郡所有年龄≥20岁的居民；符合条件的人群中有76,885人（90.3%）参与了糖尿病问题的回答。
该自治市中对糖尿病问题回答“是”的所有居民（n = 169）以及在每位糖尿病患者前后出生且性别相同、对糖尿病问题回答“否”的人员（n = 338）均被纳入。
在该自治市全科医生的医疗档案中进行了非常全面的搜索以获取相应信息。与档案相比，169人中163人被证实患有糖尿病。差异的最常见原因是肾性糖尿。338名登记的非糖尿病患者中有1人被发现患有糖尿病。糖尿病患者往往显著高估糖尿病病程。问卷回答为肯定的20例中有19例（95%）胰岛素治疗得到证实，44例口服降糖药治疗均得到证实。胰岛素和口服降糖药问题回答为否定的分别有100%和99%得到证实。
一致性显著高于10年前进行的一项类似挪威研究。对于像糖尿病这样明确的慢性疾病，患者自行填写的问卷可能是流行病学研究中非常可靠的信息来源。
