Badruddin S H, Molla A, Khurshid M, Vaz S, Hassanali S
Department of Medicine, Aga Khan University Medical Centre, Karachi.
J Pak Med Assoc. 1994 May;44(5):106-12.
Serum levels of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and triglycerides (TG) were determined on 239 school children aged 5-19 years belonging to lower middle class families. The mean TC, LDL-C, HDL-C and TG ranged from 3.70-4.37 mmol/L, 2.17-2.70 mmol/L, 0.94-1.14 mmol/L, 1.07-1.26 mmol/L respectively. In general, girls had higher TC, LDL-C and HDL-C levels. There was no significant difference in the TG levels between boys and girls. Thirty-three percent of the girls and 22% of the boys had TC level > or = 4.4 mmol/L, the level at which dietary intervention is recommended for children. Fifty-three percent of the girls and 37% of the boys had TG levels > or = than the 90th percentile of the levels for children of similar age and sex in North America. The HDL-C levels were low with 37% of the girls and 44% of boys having values < or = the 10th percentile of levels for North American children. The mean daily intake of cholesterol ranged from 241 mg to 364 mg/day. Except for the 5-9 year olds, boys had a higher cholesterol intake than girls (P < 0.005). Twenty-two percent of the boys and 32% of the girls were overweight but weight status was significantly associated with elevated TC levels only in the boys (P < 0.05). Activity level was not significantly related to TC levels but girls who were active had significantly higher HDL-C levels than girls who were sedentary (P < 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)
对239名来自中低收入家庭、年龄在5至19岁的学童测定了血清总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）和甘油三酯（TG）水平。平均TC、LDL-C、HDL-C和TG分别在3.70 - 4.37毫摩尔/升、2.17 - 2.70毫摩尔/升、0.94 - 1.14毫摩尔/升、1.07 - 1.26毫摩尔/升范围内。总体而言，女孩的TC、LDL-C和HDL-C水平较高。男孩和女孩的TG水平无显著差异。33%的女孩和22%的男孩TC水平≥4.4毫摩尔/升，这是建议对儿童进行饮食干预的水平。53%的女孩和37%的男孩TG水平≥北美同龄同性儿童水平的第90百分位数。HDL-C水平较低，37%的女孩和44%的男孩HDL-C值≤北美儿童水平的第10百分位数。胆固醇的平均每日摄入量在241毫克至364毫克/天之间。除了5至9岁年龄段的儿童，男孩的胆固醇摄入量高于女孩（P < 0.005）。22%的男孩和32%的女孩超重，但仅在男孩中，体重状况与TC水平升高显著相关（P < 0.05）。活动水平与TC水平无显著相关性，但活跃的女孩比久坐的女孩HDL-C水平显著更高（P < 0.02）。（摘要截选至250字）
