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[耻骨后根治性前列腺切除术患者膀胱尿道功能的连续评估]

[Consecutive evaluation of vesico-urethral function in patients undergoing radical retropubic prostatectomy].

作者信息

Ando M, Nagamatsu H, Morita T, Ishimaru H, Fukui I, Oshima H

机构信息

Department of Urology, Tokyo Medical and Dental University, Faculty of Medicine.

出版信息

Nihon Hinyokika Gakkai Zasshi. 1994 Jul;85(7):1059-65. doi: 10.5980/jpnjurol1989.85.1059.

Abstract

We evaluated vesico-urethral function after radical retropubic prostatectomy in 18 male patients by consecutive urodynamic studies. At the time of the operation average age was 68 years with a range between 56 to 78 years old. The follow-up period after the operation was over 12 months in all patients. Pathological stage was T1 in 2, T2 in 6, T3 in 8 and T4 in 2 patients. Urodynamic evaluation including uroflowmetry, cystometry, urethral pressure profilometry (UPP) and external anal or urethral sphincter electromyography was performed before and 1, 3, 6 and 12 months after the operation. The status of postoperative urinary incontinence was reported by the patients. Sixty-five per cent of the patients revealed the low compliance bladder less than 10 ml/cm water at one month after the operation, however, most patients had normal vesical compliance and normal cystometrogram at 12 months. Both functional profile length (FPL) and maximum urethral closure pressure (UCPmax) in UPP were markedly lowered immediately after the operation and both indexes were significantly lower even at one year after the operation than preoperative ones. Both the incidence and the degree of incontinence improved during postoperative 12 months; complete urinary control was achieved in 11 patients (61%), stress urinary incontinence was present in 6 patients (33%) and one patient (6%) was still totally incontinent. Shortening FPL was considered to be the risk factor on postoperative urinary incontinence. Resection of bilateral neurovascular bundles and lower UCPmax seemed to have the possibility of the influence on it. Low compliance bladder is also likely to be one of the factors to cause early postoperative incontinence.

摘要

我们通过连续的尿动力学研究评估了18例男性患者耻骨后根治性前列腺切除术后的膀胱尿道功能。手术时患者平均年龄为68岁,年龄范围在56至78岁之间。所有患者术后随访时间均超过12个月。病理分期为T1期2例,T2期6例,T3期8例,T4期2例。在手术前以及术后1个月、3个月、6个月和12个月进行了包括尿流率测定、膀胱测压、尿道压力描记法(UPP)以及肛门或尿道外括约肌肌电图在内的尿动力学评估。患者报告了术后尿失禁的情况。65%的患者在术后1个月时显示膀胱顺应性低,低于10 ml/cm水柱,然而,大多数患者在12个月时膀胱顺应性正常且膀胱测压图正常。UPP中的功能轮廓长度(FPL)和最大尿道闭合压(UCPmax)在术后立即显著降低,并且即使在术后1年,这两个指标仍显著低于术前水平。术后12个月内尿失禁的发生率和程度均有所改善;11例患者(61%)实现了完全控尿,6例患者(33%)存在压力性尿失禁,1例患者(6%)仍完全失禁。FPL缩短被认为是术后尿失禁的危险因素。双侧神经血管束的切除和较低的UCPmax似乎有可能对其产生影响。低顺应性膀胱也可能是导致术后早期尿失禁的因素之一。

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