Magnuson B, Hatton J, Zweng T N, Young B
Nutr Clin Pract. 1994 Aug;9(4):146-50. doi: 10.1177/0115426594009004146.
Neurosurgical patients in pentobarbital coma are a complex nutrition support population. Physiologic changes associated with the primary injury to the brain, combined with the pharmacodynamic influences of barbiturate therapy, contribute to the difficulties of initiating aggressive nutrition support. Early nutritional repletion is important to the overall outcome of traumatically injured patients. Consequently, factors that influence nutrition support decisions must be understood to assure appropriate intervention. The metabolic changes associated with traumatic head injury, pentobarbital therapy, and nutrition support strategies are reviewed.
处于戊巴比妥昏迷状态的神经外科患者是一个复杂的营养支持群体。与脑原发性损伤相关的生理变化，加上巴比妥类药物治疗的药效学影响，导致了启动积极营养支持的困难。早期营养补充对创伤患者的整体预后很重要。因此，必须了解影响营养支持决策的因素，以确保进行适当的干预。本文综述了与创伤性脑损伤、戊巴比妥治疗和营养支持策略相关的代谢变化。
