Bonnerot V, Sebag G, de Montalembert M, Wioland M, Glorion C, Girot R, Lallemand D
Department of Pediatric Radiology, Hôpital des Enfants Malades, Paris, France.
Pediatr Radiol. 1994;24(2):92-5. doi: 10.1007/BF02020160.
In order to evaluate the role of gadolinium-DOTA enhanced MRI in the management of painful osseous crises in children with sickle cell anemia (SCA), nine children with SCA underwent MRI, bone scans and ultrasonographic studies during 11 osseous crises. Imaging findings were compared with the final diagnosis: three acute osteomyelitis (AO) and 16 acute infarcts (AI). MRI could not differentiate AO from AI. The appearance of severe AI was very misleading and was similar to the usual appearance of AO, including soft tissue changes, periosteal reaction and patterns of enhancement. Gadolinium-DOTA enhanced MRI was useful for determining the anatomic site and extent of AO or AI and for distinguishing between necrotic material, fluid collection and vascularized inflammatory tissue. It can also help to guide the aspiration of intraosseous, subperiosteal and soft tissue fluid collections.
为了评估钆喷酸葡胺增强磁共振成像（MRI）在镰状细胞贫血（SCA）患儿疼痛性骨危象管理中的作用，9例SCA患儿在11次骨危象期间接受了MRI、骨扫描和超声检查。将影像学检查结果与最终诊断结果进行比较：3例急性骨髓炎（AO）和16例急性梗死（AI）。MRI无法区分AO和AI。严重AI的表现极具误导性，与AO的常见表现相似，包括软组织改变、骨膜反应和强化模式。钆喷酸葡胺增强MRI有助于确定AO或AI的解剖部位和范围，区分坏死物质、液体积聚和血管化炎症组织。它还可以帮助指导骨内、骨膜下和软组织液体积聚的抽吸。
