Vázquez G M, Ramírez J, Peña Cortés M, Iglesias Gamarra A
Unidad de Reumatología, Hospital San Juan de Dios, Universidad Nacional de Colombia.
Rev Invest Clin. 1994 Jan-Feb;46(1):63-6.
A case presentation of a patient with SLE associated with papulonodular mucinosis, generalized lymphadenopathy and splenomegaly is reported, along with a review of the literature. This 24 year old woman had biopsy-proven, skin lesions consistent with dermal mucinosis and a non-homogeneous immunofluorescence pattern. Serum anti-nuclear and anti-DNA antibodies were present and a mesangioproliferative glomerulonephritis was documented. The patient responded dramatically to standard therapy with prednisolone. The nature of the mucin deposits and the pattern of immunofluorescence deposition in the skin are discussed based on the findings reported in the literature.
