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糖尿病患者的心肌梗死

Myocardial infarction in diabetics.

作者信息

Soler N G, Bennett M A, Pentecost B L, Fitzgerald M G, Malins J M

出版信息

Q J Med. 1975 Jan;44(173):125-32.

PMID:807945
Abstract

The hospital mortality of acute myocardial infarction amongst 285 known diabetics treated in the last decade was 39.7 per cent at one month and had increased to 51 per cent at 12 months. Treatment in a coronary care unit during the acute stage had little effect on the mortality amongst patients on insulin, but was beneficial for patients whose diabetes had been controlled by oral hypoglycaemic drugs. Female patients on oral hypoglycaemic drugs had the highest mortality. When considering age, duration of diabetes and presence of retinopathy, acute myocardial infarction in diabetics controlled on oral therapy appeared to have a worse outcome than in patients on insulin. Independently of whether patients were on insulin or on oral hypoglycaemic drugs 12 months after the acute episode, only about half of them were still alive.

摘要

在过去十年中接受治疗的285名已知糖尿病患者中,急性心肌梗死的医院死亡率在1个月时为39.7%,在12个月时升至51%。急性期在冠心病监护病房治疗对胰岛素治疗患者的死亡率影响不大,但对糖尿病通过口服降糖药得到控制的患者有益。服用口服降糖药的女性患者死亡率最高。在考虑年龄、糖尿病病程和视网膜病变的存在时,口服治疗控制的糖尿病患者急性心肌梗死的预后似乎比胰岛素治疗的患者更差。急性发作12个月后,无论患者使用胰岛素还是口服降糖药,只有约一半的患者仍存活。

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