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[切尔诺贝利原子能发电站事故清理人员遭受低剂量电离辐射后的神经紊乱]

[Nervous disorders in those engaged in the cleanup of the accident at the Chernobyl Atomic Electric Power Station subjected to ionizing radiation exposure at low doses].

作者信息

Panchenko E N, Kazakova S E, Safonova E F

出版信息

Lik Sprava. 1993 Jul(8):13-6.

PMID:8079465
Abstract

Neurological, psychiatric, somatic and immune status were studied in 256 patients subjected to ionizing radiation at the dose of 10-45 cGy during liquidation of aftermath of the Chernobyl accident. In 61% of them neurocirculatory dystonia was found, 39% of patients revealed dyscirculatory encephalopathy. Alongside with dystonic disorders structural changes of vessels were detected. Asthenoneurosis diagnosed in 97% of patients was recognized as a key syndrome in 53%, while in 23%--obsessional-phobic syndrome dominated, in 7%--depressive syndrome and in 14%--psycho-organic syndrome were at the foreground. Somatic status in most patients (67%) was burdened by diseases of digestive tract. 191 patients revealed considerable immune imbalance. In 95 patients (33%) it was less pronounced and consisted in moderate decrease of TPR/TPS ratio. Degrees of immune and neurological disorders correlated closely. The conclusion was made that low-dose radiation induces primary damage of immunity and vessels with secondary nervous system involvement. That is why connection between neurological symptoms and radiation in subjects who took part in liquidation of Chernobyl accident aftermath may be considered probable only in association with immune and circulatory disorders.

摘要

对256名在切尔诺贝利事故善后清理期间受到10 - 45厘戈瑞电离辐射的患者进行了神经、精神、躯体和免疫状况研究。其中61%的患者存在神经循环性肌张力障碍,39%的患者有循环性脑病。除肌张力障碍外,还检测到血管的结构变化。97%的患者被诊断为神经衰弱,其中53%的患者以神经衰弱为主要综合征,23%以强迫恐惧症为主,7%以抑郁综合征为主,14%以精神器质性综合征为主。大多数患者(67%)的躯体状况受到消化道疾病的困扰。191名患者出现明显的免疫失衡。95名患者(33%)的免疫失衡不太明显,表现为总外周阻力/总外周顺应性比值中度下降。免疫和神经障碍程度密切相关。得出的结论是,低剂量辐射会引发免疫和血管的原发性损伤,并继发神经系统受累。这就是为什么在参与切尔诺贝利事故善后清理的人员中,只有在伴有免疫和循环障碍的情况下,才可能认为神经症状与辐射之间存在关联。

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