Dyson D A, Smith G R
Res Vet Sci. 1975 Jul;19(1):8-16.
Cattle produced humoral mouse-protective antibody (MPA) to Mycoplasma mycoides var mycoides as a result of natural infection, hyperimmunisation, vaccination with well-known strains of living vaccines or vaccination with killed cultures. Bovine MPA was distinct from complement-fixing and precipitating antibodies and was frequently detected in their absence, particularly in the sera of vaccinated--as opposed to naturally infected--cattle. In view of its defensive role in artificially-infected mice, it seems likely that such antibody plays a part in resistance to the disease in cattle. High levels of MPA followed inoculation of cattle with killed concentrated culture containing adjuvant; this finding merits further investigation, as it may lead to improved methods of vaccination.
牛由于自然感染、超免疫、用知名活疫苗株接种疫苗或用灭活培养物接种疫苗，产生了针对丝状支原体丝状亚种的体液性小鼠保护抗体（MPA）。牛MPA不同于补体结合抗体和沉淀抗体，并且在没有这些抗体时也经常检测到，特别是在接种疫苗（与自然感染相对）的牛血清中。鉴于其在人工感染小鼠中的防御作用，这种抗体似乎在牛对疾病的抵抗力中发挥作用。给牛接种含佐剂的灭活浓缩培养物后，MPA水平升高；这一发现值得进一步研究，因为它可能会带来改进的疫苗接种方法。
