给予不同全氟化合物后肝脏中巨噬细胞活性的磁力测量。

Magnetometric measurements of macrophage activity in the liver after administration of different perfluorochemicals.

作者信息

Koester M B, Lutz J

机构信息

Physiologisches Institut, Universitaet Wuerzburg, Germany.

出版信息

Adv Exp Med Biol. 1994;345:215-20. doi: 10.1007/978-1-4615-2468-7_28.

DOI:10.1007/978-1-4615-2468-7_28

PMID:8079710

Abstract

The activity of liver macrophages was evaluated using a magnetometric method after administration of different perfluorochemicals. Following treatment with perfluoroctylbromide a significant shorter time period of diminished macrophage activity was found compared with a mixture of perfluorodecalin and perfluorotripropylamine. Results obtained with the magnetometric method on liver macrophages were more sensitive compared with those of colloidal carbon clearance of total body RES.

摘要

在给予不同的全氟化合物后，使用磁力测定法评估肝巨噬细胞的活性。与全氟萘烷和全氟三丙胺的混合物相比，在用全氟辛基溴处理后，发现巨噬细胞活性降低的时间段明显更短。与全身网状内皮系统的胶体碳清除率相比，用磁力测定法获得的肝巨噬细胞结果更敏感。