Jäger L J, Lutz J
Physiologisches Institut, Universitaet Wuerzburg, Germany.
Adv Exp Med Biol. 1994;345:221-6. doi: 10.1007/978-1-4615-2468-7_29.
By means of colloidal carbon clearance loading of cells of the reticulo-endothelial system (RES) in rats was estimated after administration of perfluorochemicals. Perfluorocylbromid revealed a significant lower depression of RES function than an equally dosed (g/kg b.wt.) mixture of perfluorodecalin and perfluorotripropylamine. Compared with a magnetometrical measurement of liver macrophage activity, shorter periods of cell loading was determined.
通过胶体碳清除率评估大鼠经全氟化合物给药后网状内皮系统（RES）细胞的负荷情况。与同等剂量（克/千克体重）的全氟萘烷和全氟三丙胺混合物相比，全氟环溴化物对RES功能的抑制作用明显更低。与肝脏巨噬细胞活性的磁力测量结果相比，确定了更短的细胞负荷时间。
