Seleznev M N, Guleshov V A, Grishchenko M N, Mil'chakov V I, Belov Iu V, Gallinger E Iu, Buniatian A A
Anesteziol Reanimatol. 1994 May-Jun(3):30-2.
Halothane impact on cerebral blood flow, brain metabolism and its protective effect in ischemia have been assessed in 30 patients operated on for the occlusion of brachiocephalic arteries. The data obtained indicate that additional use of halothane in N2O:O2 anesthesia during reconstructive surgery on brachiocephalic arteries makes it possible to enhance collateral blood flow, increase retrograde pressure, and decrease O2 consumption by the brain, without considerable changes in systemic hemodynamics. In addition, the studies have shown that halothane decreases lipid peroxidation processes.
已对30例因头臂动脉闭塞而接受手术的患者评估了氟烷对脑血流量、脑代谢的影响及其在缺血中的保护作用。所获得的数据表明，在头臂动脉重建手术期间于N2O:O2麻醉中额外使用氟烷，可增强侧支血流、提高逆行压力并降低脑的氧消耗，而全身血流动力学无显著变化。此外，研究表明氟烷可减少脂质过氧化过程。
