• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

加利福尼亚州一项预付健康计划中莱姆病血清学检测的应用。

The use of serologic tests for Lyme disease in a prepaid health plan in California.

作者信息

Ley C, Le C, Olshen E M, Reingold A L

机构信息

Epidemiology Program, School of Public Health, University of California, Berkeley 94720.

出版信息

JAMA. 1994 Feb 9;271(6):460-3.

PMID:8080498
Abstract

OBJECTIVE

To determine the reason(s) why serologic tests for Lyme disease are performed, who initiates the test requests, and how the test results are used in a clinical setting.

DESIGN

Retrospective cohort.

SETTING

Prepaid health plan in northern California.

PATIENTS

Consecutive sample of 117 patients for whom at least one serologic test for Lyme disease was performed during a 3-month period.

MAIN OUTCOME MEASURES

Reason for ordering and result of the serologic test, differential diagnoses, and treatment.

RESULTS

One of 117 patients had antibodies to Borrelia burgdorferi. Fifty-six percent of test requests were initiated by the physician and 35% by the patient. Of 66 tests ordered by the physician, 20% were performed because of suspected early Lyme disease, 6% as follow-up of a tick bite, 2% to confirm a prior history of Lyme disease, 14% as a workup for arthritis, and 60% as one of a battery of laboratory tests for vague symptoms. Of 41 tests initiated by the patient, 51% were performed because of a history of a tick bite. The reasons for ordering 10 tests were undetermined.

CONCLUSION

Only 19% of all serologic tests for Lyme disease were performed because the physician suspected Lyme disease in the patient. Particularly in light of the low probability of contracting Lyme disease in California, it appears that this serologic test is being overused. Indiscriminate testing increases health care costs and does not appear to affect treatment decisions. Education is needed regarding the limitations of this serologic test.

摘要

目的

确定进行莱姆病血清学检测的原因、发起检测请求的人员以及检测结果在临床环境中的使用方式。

设计

回顾性队列研究。

地点

北加利福尼亚的预付健康计划。

患者

在3个月期间内至少进行过一次莱姆病血清学检测的117例患者的连续样本。

主要观察指标

检测的订购原因和血清学检测结果、鉴别诊断和治疗。

结果

117例患者中有1例对伯氏疏螺旋体产生抗体。56%的检测请求由医生发起,35%由患者发起。在医生订购的66项检测中,20%是因为怀疑早期莱姆病而进行的,6%是作为蜱叮咬后的随访,2%是为了确认既往莱姆病病史,14%是作为关节炎的检查,60%是作为一系列针对模糊症状的实验室检测之一。在患者发起的41项检测中,51%是因为有蜱叮咬史而进行的。10项检测的订购原因未确定。

结论

所有莱姆病血清学检测中只有19%是因为医生怀疑患者患有莱姆病而进行的。特别是考虑到在加利福尼亚感染莱姆病的可能性较低,似乎这种血清学检测被过度使用了。不加区别的检测增加了医疗成本,而且似乎并未影响治疗决策。需要就这种血清学检测的局限性进行教育。

相似文献

1
The use of serologic tests for Lyme disease in a prepaid health plan in California.加利福尼亚州一项预付健康计划中莱姆病血清学检测的应用。
JAMA. 1994 Feb 9;271(6):460-3.
2
Tick bites and Lyme disease in an endemic setting: problematic use of serologic testing and prophylactic antibiotic therapy.流行地区的蜱叮咬与莱姆病:血清学检测和预防性抗生素治疗的问题性应用。
JAMA. 1998 Jan 21;279(3):206-10. doi: 10.1001/jama.279.3.206.
3
Test for Lyme disease in a prepaid health plan.在预付健康保险计划中进行莱姆病检测。
JAMA. 1994 Jul 20;272(3):203.
4
Physician preferences in the diagnosis and treatment of Lyme disease in the United States.美国医生对莱姆病诊断和治疗的偏好。
Infection. 1996 Mar-Apr;24(2):182-6. doi: 10.1007/BF01713336.
5
Patterns of Lyme disease diagnosis and treatment by family physicians in a southeastern state.东南部某州家庭医生对莱姆病的诊断和治疗模式
J Community Health. 2002 Dec;27(6):395-402. doi: 10.1023/a:1020697017543.
6
Feedback on difficulties raised by the interpretation of serological tests for the diagnosis of Lyme disease.关于血清学检测用于莱姆病诊断的解读所引发困难的反馈。
Med Mal Infect. 2014 May;44(5):199-205. doi: 10.1016/j.medmal.2014.03.009. Epub 2014 May 1.
7
Poor Positive Predictive Value of Lyme Disease Serologic Testing in an Area of Low Disease Incidence.莱姆病血清学检测在疾病低发地区的阳性预测值较低。
Clin Infect Dis. 2015 Nov 1;61(9):1374-80. doi: 10.1093/cid/civ584. Epub 2015 Jul 20.
8
The overdiagnosis of Lyme disease.莱姆病的过度诊断
JAMA. 1993 Apr 14;269(14):1812-6.
9
[Serologic evaluation of occurrence in Poland of Lyme disease caused by infection with Borrelia burgdorferi].[对波兰由伯氏疏螺旋体感染引起的莱姆病发病情况的血清学评估]
Med Dosw Mikrobiol. 1993;45(4):487-91.
10
The overdiagnosis of Lyme disease in children residing in an endemic area.流行地区儿童莱姆病的过度诊断。
Clin Pediatr (Phila). 1994 Nov;33(11):663-8. doi: 10.1177/000992289403301105.

引用本文的文献

1
The French Society of Internal Medicine's Top-5 List of Recommendations: a National Web-Based Survey.法国内科学会的 5 项推荐清单:一项全国性网络调查。
J Gen Intern Med. 2019 Aug;34(8):1475-1485. doi: 10.1007/s11606-019-05050-2. Epub 2019 Jun 12.
2
Health care costs, utilization and patterns of care following Lyme disease.莱姆病后的医疗保健成本、利用率及护理模式。
PLoS One. 2015 Feb 4;10(2):e0116767. doi: 10.1371/journal.pone.0116767. eCollection 2015.
3
U.S. healthcare providers' experience with Lyme and other tick-borne diseases.
美国医疗服务提供者对莱姆病和其他蜱传疾病的经验。
Ticks Tick Borne Dis. 2014 Jun;5(4):404-8. doi: 10.1016/j.ttbdis.2014.01.008. Epub 2014 Apr 6.
4
Choosing wisely: the American College of Rheumatology's Top 5 list of things physicians and patients should question.明智选择:美国风湿病学会列出的医生和患者应质疑的前五件事。
Arthritis Care Res (Hoboken). 2013 Mar;65(3):329-39. doi: 10.1002/acr.21930.
5
Appropriateness of Lyme disease serologic testing.莱姆病血清学检测的适宜性。
Ann Fam Med. 2004 Jul-Aug;2(4):341-4. doi: 10.1370/afm.117.
6
Use of serum immune complexes in a new test that accurately confirms early Lyme disease and active infection with Borrelia burgdorferi.血清免疫复合物在一项新检测中的应用,该检测能准确确诊早期莱姆病以及伯氏疏螺旋体的活动性感染。
J Clin Microbiol. 2001 Sep;39(9):3213-21. doi: 10.1128/JCM.39.9.3213-3221.2001.
7
Utilization of tests for Lyme disease antibody at a university hospital.大学医院莱姆病抗体检测的应用情况。
Clin Diagn Lab Immunol. 1996 May;3(3):287-9. doi: 10.1128/cdli.3.3.287-289.1996.