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实验性男性生殖器结核——卡介苗接种保护价值评估

Experimental male genital tuberculosis-appraisal of protective value of BCG vaccination.

作者信息

Winblad B, Duchek M, Holm S

出版信息

Acta Pathol Microbiol Scand A. 1975 Jul;83(4):415-24. doi: 10.1111/j.1699-0463.1975.tb01891.x.

DOI:10.1111/j.1699-0463.1975.tb01891.x
PMID:808092
Abstract

As part of an experimental study of the spread of urogenital tuberculosis, the development of tuberculous infection was compared in vaccinated and non-vaccinated guinea pigs after challenge with Mycobacterium tuberculosis strain H37Rv into the seminal vesicle. The animals were saccrified 35 days after challenge. Morphological observations indicate that tuberculous infection in an immunized animal is retarded, but spreads by the same routes as in an nonimmunized animal. On microbial enumeration significantly lower numbers of organisms were recovered from the inoculated seminal vesicle and regional iliac lymph nodes of the BCG-vaccinated guinea pigs.

摘要

作为泌尿生殖系统结核传播实验研究的一部分,将结核分枝杆菌H37Rv株注入精囊后,对接种疫苗和未接种疫苗的豚鼠结核感染的发展情况进行了比较。攻击后35天处死动物。形态学观察表明,免疫动物的结核感染发展受到抑制,但传播途径与未免疫动物相同。微生物计数显示,从接种卡介苗的豚鼠的接种精囊和髂区淋巴结中回收的细菌数量明显较少。

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