Ruff R M, Crouch J A, Tröster A I, Marshall L F, Buchsbaum M S, Lottenberg S, Somers L M
University of California, San Francisco.
Brain Inj. 1994 May-Jun;8(4):297-308. doi: 10.3109/02699059409150981.
Neuropsychological residua are common particularly in the early stages following a minor traumatic brain injury (TBI), however, a minority of individuals complain of persistent deficits following months or years post-accident. Nine such cases are presented with little or no evidence of brain damage demonstrated according to non-functional neuroimaging (for example CT, MRI), yet their neuropsychological examinations were positive. Since the introduction of positron emission tomography (PET), which captures a functional approach, the question arose as to what extent the two techniques (i.e. PET and neuropsychological examination) are interrelated. All nine minor TBI cases revealed a corroboration between the positive neuropsychological findings confirmed on the PET. The PET procedure documented neuropathology which frequently was pronounced in the frontal and anteriotemporo-frontal regions. Moreover, no significant differences were evident between those five cases with reported loss of consciousness vs. those four cases without.
神经心理学后遗症很常见，尤其是在轻度创伤性脑损伤（TBI）后的早期阶段，然而，少数人在事故发生数月或数年之后仍抱怨存在持续的缺陷。本文报告了9例这样的病例，根据非功能性神经影像学检查（如CT、MRI），几乎没有或没有脑损伤的证据，但他们的神经心理学检查呈阳性。自从引入正电子发射断层扫描（PET）这种功能性检查方法后，就出现了这两种技术（即PET和神经心理学检查）在多大程度上相互关联的问题。所有9例轻度TBI病例在PET检查中均证实了神经心理学阳性结果之间的相互印证。PET检查记录了神经病理学情况，其病变常在额叶和前颞叶-额叶区域较为明显。此外，报告有昏迷的5例与没有昏迷的4例之间没有明显差异。
