Tao Y, Hu Y F
Department of Pathology, Sun Yat-sen University of Medical Sciences, Guangzhou.
Zhonghua Bing Li Xue Za Zhi. 1994 Apr;23(2):76-8.
Gliomatosis peritonei (GP) is the implantation of glial tissue on the peritoneal surface in patients with solid ovarian teratoma. The average age at time of biopsy was 17.4 years in this study. The largest ovarian teratoma was 30cm in diameter with an average of 21.4cm. The tumor capsules were ruptured and adhered to the omentum in 5 cases. Peritoneal dissemination was detected in one patient at the second operation 10 months after the first one. It's believed that injury to the tumor capsule may have a role in peritoneal implantation. In general, regardless of the grade of the primary ovarian teratoma, the implanted peritoneal nodules consisted exclusively of GFAP and S-100 protein positive mature astroglia. The average length of follow up was 36.2 months. One patient with GP is alive and clinically healthy 8 years and 3 months post-operatively. The authors consider GP is a benign condition and associated with an improved prognosis for solid ovarian teratoma.
腹膜胶质细胞瘤（GP）是指实性卵巢畸胎瘤患者的神经胶质组织种植于腹膜表面。本研究中活检时的平均年龄为17.4岁。最大的卵巢畸胎瘤直径为30cm，平均为21.4cm。5例患者的肿瘤包膜破裂并与大网膜粘连。1例患者在首次手术后10个月的第二次手术中检测到腹膜播散。据信肿瘤包膜损伤可能在腹膜种植中起作用。一般来说，无论原发性卵巢畸胎瘤的分级如何，植入的腹膜结节仅由GFAP和S-100蛋白阳性的成熟星形胶质细胞组成。平均随访时间为36.2个月。1例患有GP的患者术后8年3个月仍存活且临床健康。作者认为GP是一种良性疾病，与实性卵巢畸胎瘤预后改善相关。
