300株淋病奈瑟菌对青霉素和米诺环素的最低抑菌浓度
Minimum inhibitory concentrations of penicillin and minocycline for 300 isolates of N. gonorrhoeae.
作者信息
Shahidullah M, Greaves P W
出版信息
Br J Vener Dis. 1975 Aug;51(4):265-6. doi: 10.1136/sti.51.4.265.
Abstract
The minimum inhibitory concentrations of penicillin and minocycline were measured on 300 consecutive isolates of N. gonorrhoeae from patients attending the Nottingham treatment centre. 210 (70 per cent.) of these were fully sensitive to penicillin (MIC less than 0-1 mug./ml) and 89 per cent. were fully sensitive to minocycline (MIC less than 0-5 mug./ml.). Of the nine strains resistant to penicillin (MIC less than or equal to 0-5 mug./ml.), eight were also of reduced sensitivity to minocycline.
摘要
对来自诺丁汉治疗中心患者的300株连续分离的淋病奈瑟菌测定了青霉素和米诺环素的最低抑菌浓度。其中210株（70%）对青霉素完全敏感（最低抑菌浓度小于0.1微克/毫升），89%对米诺环素完全敏感（最低抑菌浓度小于0.5微克/毫升）。在9株对青霉素耐药（最低抑菌浓度小于或等于0.5微克/毫升）的菌株中，有8株对米诺环素的敏感性也降低。
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本文引用的文献
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One-capsule treatment of gonorrhea with minocycline.
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Spectinomycin in the treatment of gonorrhoea in males.壮观霉素治疗男性淋病。
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Doxycycline HC1 (Vibramycin) syrup as a single-dose oral treatment for uncomplicated urethritis in men.盐酸多西环素（强力霉素）糖浆作为男性单纯性尿道炎的单剂量口服治疗药物。
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