Silberman E K, Sussman N, Skillings G, Callanan M
Psychiatry Department, Jefferson Medical College, Philadelphia, PA 19107-4192.
Epilepsia. 1994 Jul-Aug;35(4):778-84. doi: 10.1111/j.1528-1157.1994.tb02511.x.
We investigated a possible relation between aura phenomena and psychopathology in patients with seizure disorders. Twenty-one patients with a variety of seizure types (90% with generalized seizures, 72% with complex partial seizures, CPS) were studied. Aura phenomena were evaluated with the Silberman-Post Psychosensory Phenomena Scale; psychopathology was assessed with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version (SADS-L), the Minnesota Multiple Personality Inventory (MMPI), and the Washington Psychosocial Seizure Inventory (WPSI). Psychosensory symptoms occurring in the absence of frank seizures, but not those occurring with seizures, were related to increased psychopathology (primarily mood and anxiety related) and greater time in psychiatric treatment. Psychosensory symptoms may reflect ongoing neurophysiologic dysfunction related to epilepsy and may therefore be a useful subject for further study.
我们研究了癫痫障碍患者中先兆现象与精神病理学之间的可能关系。对21例患有多种癫痫类型的患者（90%为全身性癫痫，72%为复杂部分性发作，CPS）进行了研究。使用西尔伯曼 - 波斯特心理感觉现象量表评估先兆现象；使用情感障碍和精神分裂症终身版日程表（SADS - L）、明尼苏达多相人格调查表（MMPI）以及华盛顿社会心理癫痫调查表（WPSI）评估精神病理学。在无明显癫痫发作时出现的心理感觉症状，而非癫痫发作时出现的症状，与精神病理学增加（主要与情绪和焦虑相关）以及更长的精神科治疗时间有关。心理感觉症状可能反映了与癫痫相关的持续神经生理功能障碍，因此可能是进一步研究的有用课题。
