宾斯旺格病和阿尔茨海默病中的多模态诱发电位

Multimodal evoked potentials in Binswanger's disease and Alzheimer's disease.

作者信息

Tachibana H, Kawabata K, Takeda M, Sugita M

机构信息

Fifth Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

出版信息

Int J Neurosci. 1993 Mar-Apr;69(1-4):197-206. doi: 10.3109/00207459309003330.

DOI:10.3109/00207459309003330

PMID:8083006

Abstract

Short-latency somatosensory, brainstem auditory evoked potentials and event-related potentials were studied in 9 patients with Binswanger's disease (BD), 14 patients with Alzheimer's disease (AD) and 17 normal subjects. Patients with BD had a significantly longer interpeak latency between N13 and N20 (CCT), longer interpeak latency between waves I and V (I-V IPL) and longer P300 latency than normal subjects. In particular, CCT was significantly longer in patients with BD than in those with AD. In patients with AD, only I-V IPL and P300 latency were significantly longer in normal subjects. These results demonstrate an electrophysiological difference between BD and AD.

摘要

对9例宾斯旺格病（BD）患者、14例阿尔茨海默病（AD）患者和17名正常受试者进行了短潜伏期体感诱发电位、脑干听觉诱发电位和事件相关电位研究。BD患者N13与N20之间的峰间潜伏期（CCT）明显长于正常受试者，I波与V波之间的峰间潜伏期（I-V IPL）更长，P300潜伏期也更长。特别是，BD患者的CCT明显长于AD患者。在AD患者中，只有I-V IPL和P300潜伏期明显长于正常受试者。这些结果表明BD和AD之间存在电生理差异。