de Gruijl F R, Van der Leun J C
University Hospital Utrecht, The Netherlands.
Health Phys. 1994 Oct;67(4):319-25. doi: 10.1097/00004032-199410000-00001.
The wavelength dependency of carcinogenesis is an important factor in risk assessments pertaining to sources of ultraviolet radiation, the most important of which is the sun. This wavelength dependency cannot be measured directly in humans, but it has been measured in hairless mice, and represented in an action spectrum. An estimate of the action spectrum for humans can be produced by correcting for differences in epidermal transmission between mice and humans. This carcinogenic action spectrum for humans resembles the action spectrum for ultraviolet-induced erythema (sunburn), and results in small adjustments of earlier estimates of the effects of a stratospheric ozone depletion on skin cancer incidences.
致癌作用的波长依赖性是紫外线辐射源风险评估中的一个重要因素，其中最重要的辐射源是太阳。这种波长依赖性无法在人体中直接测量，但已在无毛小鼠中进行了测量，并以作用光谱表示。通过校正小鼠和人类之间表皮透射率的差异，可以得出人类作用光谱的估计值。这种人类致癌作用光谱类似于紫外线诱发红斑（晒伤）的作用光谱，并导致对平流层臭氧消耗对皮肤癌发病率影响的早期估计值有小幅调整。
