Garcia D P, Corbett M L, Eberly S M, Joyce M R, Le H T, Karibo J M, Pence H L, Nguyen K L
Department of Pediatrics, School of Medicine, University of Louisville, KY.
J Allergy Clin Immunol. 1994 Sep;94(3 Pt 1):523-30. doi: 10.1016/0091-6749(94)90209-7.
The diagnosis of chronic sinusitis is dependent on the radiographic evidence of sinus disease.
We evaluated the performance of radiographs and computed tomographic (CT) scans for the examination of the paranasal sinuses of 91 patients of both sexes, ranging in age from 2 to 17 years, who had chronic upper respiratory tract symptoms for at least 3 months. The CT scan findings were categorized as no disease; minimal disease, and mild, moderate, and severe sinusitis.
Fifty-eight patients (63%) had chronic sinusitis: CT scan abnormalities were minimal in 17%, mild in 19%, moderate in 21%, and severe in 43%. There was a statistically significant correlation between rhinorrhea (r = 0.25, p = 0.01), cough (r = 0.27, p = 0.009), and the severity of sinus abnormality as determined by CT scan. Clinical presentation in the mild, moderate, and severe sinusitis groups (p < 0.05) was significantly different from that of the no disease group, whereas the minimal disease group had subclinical presentation (p = 0.11). Clinically significant chronic sinusitis often occurred at multiple sites: 44% of patients had pansinusitis, 50% had disease involvement of at least two sinuses, and 6% had disease in a single sinus. When sinus radiographs were compared with CT scans (n = 70 cases), radiographs could not identify minimal disease. For clinically significant sinusitis, sinus radiographs detected disease in 1 of 5 (20%) frontal sinuses, 0 of 12 (0%) sphenoidal sinuses, and 17 of 31 (54%) ethmoidal sinuses. With the minimal criteria of 40% to 50% opacification or fluid level filling of the maxillary antrum, radiographs detected disease in 37 of 49 (75%) cases. The sensitivity and specificity for a Waters view to confirm clinically significant chronic sinusitis without specifying the sites and severity were acceptable at 76% and 81%, respectively. When limited sinus CT scans were compared with full CT evaluation (n = 49 cases), limited studies detected 5 of 5 (100%) frontal, 9 of 11 (82%) sphenoidal, 14 of 19 (73%) ethmoidal, and 39 of 40 (97%) cases of maxillary sinusitis. The overall agreement was 88%.
A single Waters view is an acceptable part of the initial evaluation of pediatric chronic sinusitis; however, a limited CT scan is a better alternative.
慢性鼻窦炎的诊断依赖于鼻窦疾病的影像学证据。
我们评估了X线片和计算机断层扫描(CT)对91例年龄在2至17岁、有至少3个月慢性上呼吸道症状的男女患者鼻窦检查的性能。CT扫描结果分为无疾病、轻微疾病、轻度、中度和重度鼻窦炎。
58例(63%)患者患有慢性鼻窦炎:CT扫描异常轻微的占17%,轻度的占19%,中度的占21%,重度的占43%。流涕(r = 0.25,p = 0.01)、咳嗽(r = 0.27,p = 0.009)与CT扫描确定的鼻窦异常严重程度之间存在统计学显著相关性。轻度、中度和重度鼻窦炎组的临床表现(p < 0.05)与无疾病组显著不同,而轻微疾病组有亚临床表型(p = 0.11)。具有临床意义的慢性鼻窦炎常发生在多个部位:44%的患者患有全鼻窦炎,50%的患者至少有两个鼻窦受累,6%的患者单个鼻窦患病。当将鼻窦X线片与CT扫描(n = 70例)比较时,X线片无法识别轻微疾病。对于具有临床意义的鼻窦炎,鼻窦X线片在5个额窦中的1个(20%)、12个蝶窦中的0个(0%)以及31个筛窦中的17个(54%)检测到疾病。以上颌窦40%至50%的混浊或液平填充为最低标准,X线片在49例中的37例(75%)检测到疾病。华氏位片确认具有临床意义的慢性鼻窦炎(不指定部位和严重程度)的敏感性和特异性分别为76%和81%,是可以接受的。当将有限鼻窦CT扫描与全CT评估(n = 49例)比较时,有限研究在5个额窦中的5个(100%)、11个蝶窦中的9个(82%)、19个筛窦中的14个(73%)以及40个上颌窦中的39个(97%)检测到鼻窦炎。总体一致性为88%。
单次华氏位片是小儿慢性鼻窦炎初始评估的可接受部分;然而,有限CT扫描是更好的选择。