Perry V H, Lawson L J, Reid D M
Department of Pharmacology, University of Oxford, England.
J Leukoc Biol. 1994 Sep;56(3):399-406. doi: 10.1002/jlb.56.3.399.
Infection of the central nervous system by HIV-1 results in widespread neuropathology and neurological symptoms. The cells infected in the brain belong to the mononuclear phagocyte lineage. We review aspects of the biology of the macrophage populations associated with the central nervous system and consider their distribution, phenotype, and kinetics in relation to HIV pathology.
HIV-1感染中枢神经系统会导致广泛的神经病理学变化和神经症状。大脑中被感染的细胞属于单核吞噬细胞谱系。我们综述了与中枢神经系统相关的巨噬细胞群体生物学的各个方面，并探讨了它们在HIV病理学方面的分布、表型和动力学。
