So B H, Tamura M, Kamoshita S
Department of Pediatrics, Faculty of Medicine, University of Tokyo, Japan.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1994 Jul-Aug;35(4):312-8.
Twin pregnancies carry a greater mortality and morbidity rate than singleton pregnancies. In case of an intrauterine fetal death (IUFD), the risk of mortality and morbidity of the surviving twin is increased. The pathogenesis is usually due to twin to twin transfusion. The donor twin is hypovolemic, anemic and often shows a growth retardation or even severe enough to cause an IUFD. The recipient twin is hypervolemic, polycythemic and weighs more than its co-twin. In this paper we reported two cases of liveborn twin complicated by an IUFD of its co-twin. Both cases were monochorionic twins. The first case was born at 29 weeks and 6 days of gestation, a male infant weighed 1054 g. His co-twin was stillborn and weighed 722 g. At birth the surviving infant showed respiratory distress syndrome (RDS), anemia and bilateral periventricular echogenicity (PVE). The second case was a female infant with a gestational age of 26 weeks and 2 days and weighed 850 g. Her stillborn co-twin weighed 804 g. Both twins showed signs of hydrops, and the liveborn infant had RDS, marked anemia (Hb 6 g/dl) and hypoalbuminemia. We will discuss the possible pathogenesis in our cases and also review some literature.
双胎妊娠比单胎妊娠具有更高的死亡率和发病率。在发生宫内胎儿死亡(IUFD)的情况下,存活胎儿的死亡和发病风险会增加。其发病机制通常是由于双胎输血。供血胎儿血容量减少、贫血,常表现为生长受限,甚至严重到导致宫内胎儿死亡。受血胎儿血容量过多、红细胞增多,体重比其同胞胎儿重。本文报道了两例存活双胎合并其同胞胎儿宫内胎儿死亡的病例。两例均为单绒毛膜双胎。第一例在妊娠29周6天时出生,为一名男婴,体重1054克。其同胞胎儿为死产,体重722克。出生时,存活婴儿表现出呼吸窘迫综合征(RDS)、贫血和双侧脑室周围回声增强(PVE)。第二例是一名女婴,孕周为26周2天,体重850克。其死产的同胞胎儿体重804克。两个胎儿均有水肿迹象,存活婴儿患有呼吸窘迫综合征、严重贫血(血红蛋白6克/分升)和低蛋白血症。我们将讨论我们病例中可能的发病机制,并回顾一些文献。