Ueda T, Yamauchi T, Kokuho M, Ishibashi K, Kawakami S, Yonese J, Kawai T
Department of Urology, Cancer Institute Hospital.
Hinyokika Kiyo. 1993 Dec;39(12):1183-6.
A case of metastatic infantile yolk sac tumor of testis is reported herein. The patient was 23 months old with a painless swelling of the right scrotal contents. Histological examination revealed yolk sac tumor. Six months later, the serum alpha-fetoprotein (AFP) was re-elevated and solitary lung metastasis had developed. After 4 courses of chemotherapy with cisplatin (CDDP), vincristine (VCR), methotrexate (MTX), peplomycin (PEP) and Etoposide (COMPE), serum AFP was normalized and lung metastasis disappeared. He has shown no evidence of disease for 5 years with normal physical growth. Aggressive chemotherapy including CDDP might be used for Stage III infantile testicular cancer.
本文报告一例睾丸转移性婴幼儿卵黄囊瘤。患者23个月大,右侧阴囊内容物无痛性肿胀。组织学检查显示为卵黄囊瘤。6个月后,血清甲胎蛋白(AFP)再次升高,且出现了孤立性肺转移。在用顺铂(CDDP)、长春新碱(VCR)、甲氨蝶呤(MTX)、培普利欧霉素(PEP)和依托泊苷(COMPE)进行4个疗程的化疗后,血清AFP恢复正常,肺转移消失。他身体生长正常,5年来未出现疾病迹象。包括CDDP在内的积极化疗可用于Ⅲ期婴幼儿睾丸癌。