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使用磁共振成像对动脉内注射淋巴细胞治疗淋巴水肿进行定量评估。

Quantitative evaluation of intraarterial lymphocyte injection therapy for lymph edema using MR imaging.

作者信息

Harada M, Amano Y, Matsuzaki K, Hayashi Y, Nishitani H, Yoshizumi M, Yoshida O, Katoh I

机构信息

Department of Radiology, School of Medicine, University of Tokushima, Japan.

出版信息

Acta Radiol. 1994 Sep;35(5):405-8.

PMID:8086242
Abstract

Five patients with unilateral leg lymph edema had intraarterial injections of lymphocytes in the affected leg with consequent improvement in 3. To assess the degree of lymph edema, T2 and intensity ratio between the 2 legs in STIR images were used. Mean and SD of T2 values in the subcutaneous tissue were measured using a triple echo sequence and found larger on the edematous side than in the opposite extremity. The mean T2 shortening obtained after the lymphocyte therapy correlated well with the reduction of limb circumference. Mean T2 reflects the fluid content, and SD of T2 the fluid distribution in the subcutaneous tissue. The degree of lymph edema and the effect of therapy can be evaluated quantitatively by measuring the value of the T2 relaxation time.

摘要

5例单侧腿部淋巴水肿患者在患侧腿部进行了动脉内淋巴细胞注射,结果3例病情有所改善。为评估淋巴水肿的程度,采用了T2以及短TI反转恢复(STIR)图像中双腿之间的强度比。使用三重回波序列测量皮下组织中T2值的均值和标准差,发现水肿侧大于对侧肢体。淋巴细胞治疗后获得的平均T2缩短与肢体周长的减小密切相关。平均T2反映了液体含量,而T2的标准差反映了皮下组织中的液体分布。通过测量T2弛豫时间的值,可以定量评估淋巴水肿的程度和治疗效果。

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