Holland D J, Chen S C, Chew W W, Gilbert G L
Centre for Infectious Diseases and Microbiology, Westmead Hospital, New South Wales, Australia.
Clin Infect Dis. 1994 Jun;18(6):1002-3. doi: 10.1093/clinids/18.6.1002.
Mycobacterium neoaurum is a rapidly growing mycobacterium that has only once before been reported as a cause of bacteremia in an immunocompromised patient. We report on a patient who developed bacteremia after an allogeneic bone marrow transplantation and from whose blood (taken via a Hickman catheter) M. neoaurum was isolated on three separate occasions. There was a clinical response to therapy with ticarcillin/clavulanate and tobramycin, and the organism appeared to be susceptible to the former in vitro. The Hickman catheter was removed because of persistence of the organism in cultures of blood taken from the catheter. M. neoaurum may be a rare cause of infections in immunocompromised patients and should not be dismissed as an environmental contaminant.
新金色分枝杆菌是一种生长迅速的分枝杆菌，此前仅有一次被报道为免疫功能低下患者菌血症的病因。我们报告了一名在异基因骨髓移植后发生菌血症的患者，从其血液（通过希克曼导管采集）中三次分别分离出新金色分枝杆菌。患者对替卡西林/克拉维酸和妥布霉素治疗有临床反应，且该菌体外对前者似乎敏感。由于从导管采集的血液培养物中持续存在该菌，故拔除了希克曼导管。新金色分枝杆菌可能是免疫功能低下患者感染的罕见病因，不应将其视为环境污染物而不予考虑。
