Lai Chih-Cheng, Tan Che-Kim, Chen Chung-Chih, Hsueh Po-Ren
Yi-Min Hospital, Taipei, Taiwan.
Int J Infect Dis. 2009 Sep;13(5):e276-8. doi: 10.1016/j.ijid.2008.11.001. Epub 2008 Dec 31.
Mycobacterium neoaurum, a member of the Mycobacterium parafortuitum complex, has only rarely been reported as a pathogen of human infections. We report a case of catheter-related bloodstream infection (CRBSI) due to M. neoaurum in a patient on hemodialysis. The isolate was identified by conventional methods as well as by 16S rRNA gene analysis. The patient was successfully treated with intravenous antibiotics (meropenem and amikacin) for three weeks and the catheter was removed. M. neoaurum should be considered as a possible cause of CRBSI in patients with renal failure. Combination antimicrobial therapy and catheter removal can lead to a favorable clinical outcome.
新金色分枝杆菌是偶然分枝杆菌复合体的成员,作为人类感染病原体的报道极为罕见。我们报告了1例血液透析患者发生的由新金色分枝杆菌引起的导管相关血流感染(CRBSI)。通过传统方法以及16S rRNA基因分析对分离菌株进行了鉴定。患者接受静脉抗生素(美罗培南和阿米卡星)治疗3周,导管被拔除,治疗成功。对于肾衰竭患者,应考虑新金色分枝杆菌为CRBSI的可能病因。联合抗菌治疗及拔除导管可带来良好的临床结局。