Gersing E, Osypka M
Zentrum Physiologie und Pathophysiologie, Universität, Göttingen, Germany.
Physiol Meas. 1994 May;15 Suppl 2a:A21-8. doi: 10.1088/0967-3334/15/2a/003.
The electrical impedance is a characteristic tissue property that can be used for imaging cross sections of the body. The full information contained in the complex tissue impedance can be utilized if not only the real part Re(Z) or the magnitude of the impedance but also the imaginary part Im(Z) or the phase is considered. Impedance measurements provide information about tissue structure, particularly extracellular space and cell membranes. Therefore, an electrical impedance tomograph was constructed which uses alternatively the real component, the imaginary component, the magnitude or the phase in an extended frequency range. The components are evaluated by digital correlation. The device allows state-different or frequency-different (almost static) imaging. 16 electrodes are used. Image reconstruction is arrived at by a back-projection algorithm. For frequency-different imaging the measured imaginary part values can be used after normalization (division by the measuring frequency); instead of the phase values, the quotients Im(Z)/Re(Z) are taken and divided by the actual frequency, representing time constants of the tissue. Frequency-different measurements on a tank filled with saline containing a metallic rod and an insulator show in a very illustrative manner the impedance of the metal/electrolyte boundary layer (phenomenon of electrode polarization). The first in vivo measurements are very promising, state-different as well as frequency-different images of the human thorax represent, for example, the lungs with higher contrast using the phase than using the magnitude.(ABSTRACT TRUNCATED AT 250 WORDS)
电阻抗是一种组织特性,可用于对人体横截面进行成像。如果不仅考虑复组织阻抗的实部Re(Z)或阻抗幅值,还考虑虚部Im(Z)或相位,那么复组织阻抗中包含的全部信息都可以得到利用。阻抗测量可提供有关组织结构的信息,尤其是细胞外间隙和细胞膜的信息。因此,构建了一种电阻抗断层扫描仪,它在扩展的频率范围内交替使用实部、虚部、幅值或相位。这些分量通过数字相关进行评估。该设备可以进行状态不同或频率不同(几乎是静态)的成像。使用16个电极。通过反投影算法进行图像重建。对于频率不同的成像,测量得到的虚部值在归一化(除以测量频率)后可以使用;代替相位值,取Im(Z)/Re(Z)的商并除以实际频率,其代表组织的时间常数。在一个装有含金属棒和绝缘体的盐水的水箱上进行的频率不同的测量非常直观地显示了金属/电解质边界层的阻抗(电极极化现象)。首次体内测量很有前景,例如,人体胸部的状态不同和频率不同的图像显示,使用相位比使用幅值时肺部的对比度更高。(摘要截取自250字)