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18年中破伤风111例。经验报告及总结(作者译)

[111 cases of tetanus in 18 years. Report of experiences and general conclusions (author's transl)].

作者信息

Haid B

出版信息

MMW Munch Med Wochenschr. 1975 Jul 4;117(27):1149-58.

PMID:808709
Abstract

Tetanus is subdivided into 3 degrees of severity according to the course. When death occurs, we differentiate those cases due to the disease itself (16) and those resulting from late complications or avoidable technical defects (12). 82 of our 111 patients-79 men and women-had been neither passively nor actively immunized and none of the supposedly actively immunized had been inoculated properly. The horse serum available in earlier years was considered unsuitable while an intravenous human serum recently produced by Messrs Immuno of Vienna justified greater expectations. Sedation or prolonged sleep with and without relaxation, tube feeding and parenteral feeding, prolonged intubation or trachectomy, duration of the life-threatening phase of the disease, breaking off treatment ("stealing out"), mobilization and finally, the question of expense, bear no relation to the extremely small cost of a confirmed triple inoculation. An urgent consequence of this is obligatory active immunization in early childhood if an earlier inoculation has not been done, but also at any time afterwards.

摘要

破伤风根据病程分为3度严重程度。当发生死亡时,我们区分因疾病本身导致的病例(16例)和因晚期并发症或可避免的技术缺陷导致的病例(12例)。我们的111例患者中,有82例(79名男性和女性)既未接受被动免疫也未接受主动免疫,而那些所谓接受主动免疫的患者也没有正确接种。早年可用的马血清被认为不合适,而维也纳Immuno公司最近生产的静脉用人血清更值得期待。镇静或延长睡眠(无论是否伴有肌肉松弛)、管饲和胃肠外营养、延长插管或气管切开术、疾病危及生命阶段的持续时间、中断治疗(“偷偷溜走”)、动员,最后还有费用问题,与确认的三联接种极低的成本毫无关系。由此产生的一个紧迫后果是,如果早期未进行接种,幼儿期必须进行主动免疫,而且之后的任何时候也都必须进行。

相似文献

1
[111 cases of tetanus in 18 years. Report of experiences and general conclusions (author's transl)].18年中破伤风111例。经验报告及总结(作者译)
MMW Munch Med Wochenschr. 1975 Jul 4;117(27):1149-58.
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引用本文的文献

1
Dysfunction of the sympathetic nervous system in tetanus. A study of 3 cases.破伤风时交感神经系统功能障碍。3例研究。
Klin Wochenschr. 1979 Apr 17;57(8):391-5. doi: 10.1007/BF01480477.
2
[Neurologic-psychiatric follow-up studies of reanimated tetanus patients (author's transl)].
Z Rechtsmed. 1977 Jan 21;79(1):7-11. doi: 10.1007/BF00204538.
3
The involvement of the sympathetic nervous system in tetanus.
Klin Wochenschr. 1979 Apr 17;57(8):383-9. doi: 10.1007/BF01480476.