Suppr超能文献

由二斑叶螨(红蜘蛛螨)引起的职业性鼻结膜炎和哮喘。病例报告。

Occupational rhinoconjunctivitis and asthma caused by Tetranychus urticae (red spider mite). A case report.

作者信息

Delgado J, Gómez E, Palma J L, González J, Monteseirin F J, Martínez A, Martínez J, Conde J

机构信息

Servicio regional de Inmunología Alergia, Hospital Universitario Virgen Macarena, Sevilla, Spain.

出版信息

Clin Exp Allergy. 1994 May;24(5):477-80. doi: 10.1111/j.1365-2222.1994.tb00937.x.

Abstract

This paper highlights a clinical case of a patient suffering bronchial asthma and rhinoconjunctivitis due to sensitization to Tetranychus urticae (TU), commonly known as the red spider mite, which belongs to the Prostigmata sub-order of the Tetranychidae family, in relation to a work environment (a carnation nursery). Both prick and intradermal skin tests were positive, as well as specific bronchial challenge tests with TU extract. Specific IgE was demonstrated by RAST (Class 3). Unspecific bronchial provocation with methacholine was negative. Sodium dodecylsulfate-polyacrylamide gel electrophoresis (SDS-PAGE) immunoblotting revealed the presence of seven main IgE binding proteins, the more intense bands being those appearing at 21, 17 and 15 kDa. This indicates a case of immediated type hypersensitivity to Tetranychus urticae with a clear correlation to occupational environment.

摘要

本文着重介绍了一名因对二斑叶螨(Tetranychus urticae,俗称红蜘蛛螨)致敏而患有支气管哮喘和鼻结膜炎的临床病例,该螨属于叶螨科前气门亚目,与工作环境(康乃馨苗圃)有关。点刺试验和皮内试验均呈阳性,用二斑叶螨提取物进行的特异性支气管激发试验也呈阳性。通过放射性变应原吸附试验(RAST,3级)证实了特异性IgE的存在。用乙酰甲胆碱进行的非特异性支气管激发试验为阴性。十二烷基硫酸钠-聚丙烯酰胺凝胶电泳(SDS-PAGE)免疫印迹显示存在七种主要的IgE结合蛋白,其中强度较高的条带出现在21、17和15 kDa处。这表明该病例为对二斑叶螨的速发型超敏反应,且与职业环境有明显关联。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验