Takeshita H, Yasuda T, Nadano D, Tenjo E, Sawazaki K, Iida R, Kishi K
Department of Legal Medicine, Fukui Medical School, Japan.
Int J Biochem. 1994 Aug;26(8):1025-31. doi: 10.1016/0020-711x(94)90074-4.
Deoxyribonucleases (DNases) I and II activities in 13 different organs and body fluids from healthy male rabbits were measured using the single radial enzyme diffusion method. We now show that testis, epididymis, ampulla, seminal vesicle, vesicular gland, prostate, and semen have both of the DNases I and II activities, whereas spermatozoa do not. DNase I activities were highest in epididymis and seminal vesicle, whereas DNase II activities were highest in epididymis and prostate among the reproductive organs. The presence of these two enzyme activities outside the digestive system suggests that they have another biological function in addition to their digestive roles.
采用单向放射酶扩散法测定了健康雄兔13种不同器官和体液中的脱氧核糖核酸酶（DNase）Ⅰ和Ⅱ活性。我们现在发现，睾丸、附睾、壶腹、精囊、泡状腺、前列腺和精液中同时存在DNaseⅠ和Ⅱ活性，而精子中则没有。在生殖器官中，附睾和精囊中的DNaseⅠ活性最高，而附睾和前列腺中的DNaseⅡ活性最高。这两种酶活性在消化系统外的存在表明，它们除了具有消化作用外，还具有其他生物学功能。
