Moe A A, Hardy W D
Center for Clinical AIDS Research and Education, University of California School of Medicine, Los Angeles.
Infect Dis Clin North Am. 1994 Jun;8(2):331-64.
In this article, Pneumocystis carinii pneumonia (PCP) in persons with AIDS is described with regard to its epidemiology, pathogenesis, presentation, treatment, and prophylaxis. The changing epidemiologic patterns of PCP from 1981 to 1993 are diagrammed. Atypical and classical presentations of pre-AIDS, including extrapulmonary Pneumocystis, are discussed. Diagnostic strategies are outlined, giving algorithms for the most efficient means of diagnosing PCP. Various intravenous and oral treatment options for pneumonia, the use of adjunctive corticosteroids, and comparison of various prophylactic regimens are also presented in this article.
本文描述了艾滋病患者的卡氏肺孢子虫肺炎（PCP），涉及到其流行病学、发病机制、临床表现、治疗和预防。文中绘制了1981年至1993年PCP不断变化的流行病学模式图。讨论了艾滋病前期的非典型和典型表现，包括肺外卡氏肺孢子虫感染。概述了诊断策略，并给出了诊断PCP最有效方法的算法。本文还介绍了肺炎的各种静脉和口服治疗方案、辅助性皮质类固醇的使用以及各种预防方案的比较。
