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南非黑人和津巴布韦人中的多发性硬化症。

Multiple sclerosis in black South Africans and Zimbabweans.

作者信息

Dean G, Bhigjee A I, Bill P L, Fritz V, Chikanza I C, Thomas J E, Levy L F, Saffer D

机构信息

Medico-Social Research Board, Dublin, Ireland.

出版信息

J Neurol Neurosurg Psychiatry. 1994 Sep;57(9):1064-9. doi: 10.1136/jnnp.57.9.1064.

DOI:10.1136/jnnp.57.9.1064
PMID:8089669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1073127/
Abstract

Multiple sclerosis is rare among the indigenous black people of Africa. The first account of a black patient with multiple sclerosis in South Africa was published as late as 1987. Since then a search to find black patients with multiple sclerosis in Southern Africa has continued. Seven black patients have now been traced in South Africa and five in Zimbabwe in whom a diagnosis of multiple sclerosis can be accepted. Six of the 12 patients became blind, or nearly so, from severe optic neuritis. Multiple sclerosis in these few black patients more often resembled the disorder as it occurs in oriental people than among white people in southern Africa or the black people of North America or the Caribbean.

摘要

多发性硬化症在非洲本土黑人中较为罕见。南非首例关于黑人多发性硬化症患者的报道直到1987年才发表。从那时起,人们一直在南非寻找患有多发性硬化症的黑人患者。目前已在南非追踪到7名黑人患者,在津巴布韦追踪到5名,他们的多发性硬化症诊断可以被认可。这12名患者中有6人因严重视神经炎而失明或几乎失明。这少数黑人患者的多发性硬化症与东方人患的这种疾病更为相似,而不像南非的白人、北美或加勒比地区的黑人所患的疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e55/1073127/b7be9379c542/jnnpsyc00039-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e55/1073127/1b241ae60cd2/jnnpsyc00039-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e55/1073127/b7be9379c542/jnnpsyc00039-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e55/1073127/1b241ae60cd2/jnnpsyc00039-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e55/1073127/b7be9379c542/jnnpsyc00039-0046-a.jpg

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1
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Br Med J. 1949 May 14;1(4610):842-5. doi: 10.1136/bmj.1.4610.842.
2
Motor neuron disease and multiple sclerosis mortality in Australia, New Zealand and South Africa compared with England and Wales.澳大利亚、新西兰和南非与英格兰及威尔士的运动神经元病和多发性硬化症死亡率比较。
J Neurol Neurosurg Psychiatry. 1993 Jun;56(6):633-7. doi: 10.1136/jnnp.56.6.633.
3
Multiple sclerosis in Mulago Hospital, Uganda.
不同种族和民族的多发性硬化症患者的磁共振成像特征是否存在差异?
Front Neurol. 2023 Jun 28;14:1215774. doi: 10.3389/fneur.2023.1215774. eCollection 2023.
4
Navigating the journey of multiple sclerosis management in Africa, overcoming hurdles and harnessing opportunities: a review.非洲多发性硬化症管理之旅:克服障碍与把握机遇的综述
Ann Med Surg (Lond). 2023 Apr 6;85(5):1774-1779. doi: 10.1097/MS9.0000000000000560. eCollection 2023 May.
5
Multiple sclerosis in Kenya: Demographic and clinical characteristics of a registry cohort.肯尼亚的多发性硬化症:登记队列的人口统计学和临床特征
Mult Scler J Exp Transl Clin. 2021 Jun 14;7(2):20552173211022782. doi: 10.1177/20552173211022782. eCollection 2021 Apr-Jun.
6
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Neuromolecular Med. 2021 Mar;23(1):86-98. doi: 10.1007/s12017-020-08629-9. Epub 2020 Nov 18.
7
The neuromyelitis optica presentation and the aquaporin-4 antibody in HIV-seropositive and seronegative patients in KwaZulu-Natal, South Africa.南非夸祖鲁-纳塔尔省HIV血清阳性和血清阴性患者中的视神经脊髓炎表现及水通道蛋白4抗体
South Afr J HIV Med. 2017 Jan 31;18(1):684. doi: 10.4102/sajhivmed.v18i1.684. eCollection 2017.
8
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Middle East Afr J Ophthalmol. 2017 Jul-Sep;24(3):131-135. doi: 10.4103/meajo.MEAJO_133_17.
9
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Mult Scler J Exp Transl Clin. 2016 Jul 4;2:2055217316657117. doi: 10.1177/2055217316657117. eCollection 2016 Jan-Dec.
10
Post-traumatic acute disseminated encephalomyelitis.创伤后急性播散性脑脊髓炎
Radiol Case Rep. 2015 Dec 7;7(3):584. doi: 10.2484/rcr.v7i3.584. eCollection 2012.
乌干达穆拉戈医院的多发性硬化症
East Afr Med J. 1980 Apr;57(4):262-6.
4
Multiple sclerosis and neuromyelitis optica. Case report and speculation.多发性硬化症与视神经脊髓炎。病例报告及推测。
S Afr Med J. 1981 Aug 8;60(6):249-51.
5
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6
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7
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10
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S Afr Med J. 1987 Dec 19;72(12):873-5.