与抗DNA抗体相关的复发性视神经脊髓炎。
Recurrent opticomyelitis associated with anti-DNA antibody.
作者信息
Kira J, Goto I
机构信息
Department of Neurology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
出版信息
J Neurol Neurosurg Psychiatry. 1994 Sep;57(9):1124-5. doi: 10.1136/jnnp.57.9.1124.
Abstract
Two patients had frequent attacks of acute myelitis and optic neuritis. One patient lacked any other organ involvement whereas the other developed systemic manifestations of systemic lupus erythematosus 14 years after the onset. Both patients developed antinuclear and antidouble strand DNA antibodies after the onset of neurological involvement. These patients, whose neurological manifestations were indistinguishable from multiple sclerosis, were thus considered to have systemic lupus erythematosus related collagen disease.
摘要
两名患者频繁发作急性脊髓炎和视神经炎。一名患者无其他器官受累，而另一名患者在发病14年后出现了系统性红斑狼疮的全身表现。两名患者在神经受累发作后均出现抗核抗体和抗双链DNA抗体。这些患者的神经表现与多发性硬化症难以区分，因此被认为患有系统性红斑狼疮相关的胶原病。
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