Wang T N, Chang S J, Ko Y C
Aboriginal Health Laboratory, School of Public Health, Kaohsiung Medical College, Taiwan, Republic of China.
Gaoxiong Yi Xue Ke Xue Za Zhi. 1994 Jul;10(7):392-404.
Standardized incidence ratios (SIR) of malignant neoplasms in Taiwanese Aborigines were analyzed. In all, 995 cases of cancers had been reported in 30 Taiwanese Aboriginal communities between 1981 and 1987. In the same time period, 137, 159 cases were registered in Taiwan and carefully categorized according to race, gender, site and frequency of occurrence. Sex and tribe-specific standardized incidence ratios with 95% confidence interval were calculated. We found that the standardized incidence ratios of all cancers in Aborigines was lower than that in the general population of Taiwan for both Aboriginal men (0.72, 95% CI:0.67-0.78) and women (0.66, 95% CI:0.59-0.72). Of selected malignant neoplasms, SIR for nasopharyngeal carcinoma was slightly elevated in men, especially in the Bunun and Rukai tribes and significantly elevated in Paiwan women (2.95, 95% CI:1.65-4.87). The SIR for gastric cancer was significantly elevated for both men (SIR = 1.22, 95% CI:1.03-1.44) and women (1.48, 95% CI:1.14-1.92), especially in Atayal and Bunun men and Atayal women. There was a higher than expected level of incidence of penis cancer and other male genital cancers, especially in Paiwan people, with the SIR as large as 6.24 (95% CI:2.02-14.53). The SIR of lymph node cancer was significantly increased in Bunun (4.21, 95% CI:1.36-9.81) and Yamei women (CI:1.50-44.89), but not for all Aboriginal men. Colon, rectum, lung, bladder and oral cancers in aboriginal men and colon, rectum, lung, breast and cervical cancer in women occurred significantly less frequently than in the general population. The SIR of colon and rectum carcinoma was significant lower for both men (0.45, 95% CI:0.32-0.61) and women (0.25, 95% CI:0.13-0.42), particularly in the Atayal and Paiwan tribes. The SIR of lung cancer was 0.52 (95% CI:0.41-0.66) in Atayal, Bunun, Paiwan men and 0.58 (95% CI:0.38-0.86) in Paiwan women. There were significantly lower than expected levels of incidence of bladder (0.18, 95% CI:0.02-0.65) and oral cancer (0.29, 95% CI:0.08-0.74) for Atayal men. Aboriginal women had significantly lower SIR of cervical cancer (0.46) especially in Atayal, Bunun, Paiwan women and of breast cancer (0.38) especially in the Atayal and Paiwan women. But cancer of esophagus, liver, gallbladder, pancreas, and prostate occurred among Aboriginal people at the same rate as in the general Taiwan.
分析了台湾原住民恶性肿瘤的标准化发病比（SIR）。1981年至1987年期间，30个台湾原住民社区共报告了995例癌症病例。在同一时期，台湾登记了137159例病例，并根据种族、性别、部位和发病频率进行了仔细分类。计算了性别和部落特异性标准化发病比及其95%置信区间。我们发现，原住民男性（0.72，95%CI：0.67 - 0.78）和女性（0.66，95%CI：0.59 - 0.72）所有癌症的标准化发病比均低于台湾普通人群。在选定的恶性肿瘤中，男性鼻咽癌的SIR略有升高，尤其是布农族和鲁凯族，排湾族女性的SIR显著升高（2.95，95%CI：1.65 - 4.87）。胃癌的SIR在男性（SIR = 1.22，95%CI：1.03 - 1.44）和女性（1.48，95%CI：1.14 - 1.92）中均显著升高，尤其是泰雅族和布农族男性以及泰雅族女性。阴茎癌和其他男性生殖器官癌症的发病率高于预期水平，尤其是在排湾族中，SIR高达6.24（95%CI：2.02 - 14.53）。布农族（4.21，95%CI：1.36 - 9.81）和雅美族女性（CI：1.50 - 44.89）淋巴结癌的SIR显著升高，但并非所有原住民男性都是如此。原住民男性的结肠癌、直肠癌、肺癌、膀胱癌和口腔癌以及女性的结肠癌、直肠癌、肺癌、乳腺癌和宫颈癌的发病频率显著低于普通人群。男性结肠癌和直肠癌的SIR显著低于女性（0.45，95%CI：0.32 - 0.61）和女性（0.25，95%CI：0.13 - 0.42），尤其是在泰雅族和排湾族部落。泰雅族、布农族、排湾族男性肺癌的SIR为0.52（95%CI：0.41 - 0.66），排湾族女性为0.58（95%CI：0.38 - 0.86）。泰雅族男性膀胱癌（0.18，95%CI：0.02 - 0.65）和口腔癌（0.29，95%CI：0.08 - 0.74）的发病率显著低于预期水平。原住民女性宫颈癌的SIR显著较低（0.46），尤其是在泰雅族、布农族、排湾族女性中，乳腺癌的SIR（0.38），尤其是在泰雅族和排湾族女性中。但原住民中食管癌、肝癌、胆囊癌、胰腺癌和前列腺癌的发病率与台湾普通人群相同。
