[一名通过聚合酶链反应（PCR）方法早期诊断为军团菌肺炎的患者]

[A patient with Legionella pneumonia diagnosed early by the PCR method].

作者信息

Tanaka H, Miyajima K, Asano K, Kambara K, Arakawa M, Ito H

机构信息

Second Department of Internal Medicine, Gifu University, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Jun;32(6):591-5.

PMID:8089949

Abstract

A 72-year-old man was admitted to our hospital because of acute respiratory failure. Initially he had been diagnosed as having pneumonia in the lower left lung field and treated with cephem antibiotics by a local physician. Chest X-ray photograph revealed wide-spread infiltrates throughout both lungs, and chest CT scan revealed pleural effusions. The partial pressure of oxygen in arterial blood was 45.8 Torr. In the bronchoalveolar lavage fluid (BALF) specimen, legionella DNA was detected by the polymerase chain reaction (PCR) method. Thus, we were able to diagnose Legionella pneumonia immediately, and to treat the patient successfully.

摘要

一名72岁男性因急性呼吸衰竭入住我院。最初，当地医生诊断他左下肺叶患有肺炎，并使用头孢菌素类抗生素进行治疗。胸部X光片显示双肺广泛浸润，胸部CT扫描显示有胸腔积液。动脉血氧分压为45.8托。在支气管肺泡灌洗（BALF）液标本中，通过聚合酶链反应（PCR）方法检测到军团菌DNA。因此，我们能够立即诊断出军团菌肺炎，并成功治疗了该患者。