[一例伴有自身免疫性溶血性贫血的寻常型间质性肺炎]

[A case of UIP with autoimmune hemolytic anemia].

作者信息

Inoue R, Kado T, Takada Y, Ohbayashi K, Yamamoto H

机构信息

Department of Respiratology, Hyogo Medical Center for Adults.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Jun;32(6):596-601.

PMID:8089950

Abstract

A 70-year-old male was admitted because of cough and sputum. Chest X-ray showed bilateral interstitial shadows, and usual interstitial pneumonitis was diagnosed by TBLB and BAL. He was followed without medication. The dyspnea increased and the abnormal shadow spread on chest X-ray. Autoimmune hemolytic anemia was newly diagnosed because the RBC count was 195 x 10(4)/mm3, Hb was 8.6 g/dl, and direct Coombs test and warm antibody were positive. In this case, there appears to be a relationship between deterioration of interstitial pneumonia and the on-set of autoimmune hemolytic anemia.

摘要

一名70岁男性因咳嗽、咳痰入院。胸部X线显示双侧间质性阴影，经经支气管肺活检（TBLB）和支气管肺泡灌洗（BAL）诊断为普通型间质性肺炎。他未接受药物治疗，而是接受随访观察。后来呼吸困难加重，胸部X线显示异常阴影扩大。由于红细胞计数为195×10⁴/mm³，血红蛋白为8.6g/dl，直接抗人球蛋白试验和温抗体均呈阳性，故新诊断出自身免疫性溶血性贫血。在这种情况下，间质性肺炎的恶化与自身免疫性溶血性贫血的发病之间似乎存在关联。