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Philadelphia chromosome positive acute lymphoblastic leukemia masquerading as persistent asymptomatic bone marrow necrosis.

作者信息

Kwong Y L, Pollock A, Wei D, Lie A K

机构信息

University Department of Medicine, Queen Mary Hospital, Hong Kong.

出版信息

Pathology. 1994 Apr;26(2):183-5. doi: 10.1080/00313029400169441.

Abstract

Bone marrow necrosis is an uncommon histologic finding of malignant diseases at presentation. Clinically it is characterized by pyrexia and severe bone pain, and heralds a poor prognosis if untreated. We report an unusual patient with asymptomatic bone marrow necrosis persisting for 10 mths, a hitherto undescribed length of time for this condition. The diagnosis of Philadelphia chromosome positive acute lymphoblastic leukemia was finally made after multiple bone marrow biopsies.

摘要

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