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[心房利钠肽在左心室室壁瘤心肌细胞中的表达]

[The expression of atrial natriuretic peptide in the cardiomyocytes of left ventricular aneurysms].

作者信息

Fernández González A L, Montuenga L, Herreros J M

机构信息

Servicio de Cirugía Cardiovascular, Clínica Universitaria, Pamplona.

出版信息

Rev Esp Cardiol. 1994 Jul;47(7):500-2.

PMID:8090979
Abstract

We report three patients with left ventricular aneurysm who underwent coronary artery bypass grafting and resection of the ventricular aneurysm. The walls of the aneurysms were immunohistochemically investigated to study whether atrial natriuretic peptide was present or not. Immunoreactivity for atrial natriuretic peptide was observed in some of the viable cardiomyocytes within the scar tissue. Mechanisms of regulation of the expression of atrial natriuretic peptide are discussed.

摘要

我们报告了3例接受冠状动脉旁路移植术及心室壁瘤切除术的左心室壁瘤患者。对瘤壁进行免疫组织化学研究,以探讨心房利钠肽是否存在。在瘢痕组织内的一些存活心肌细胞中观察到了心房利钠肽的免疫反应性。文中讨论了心房利钠肽表达的调节机制。

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