Flannery M T, Espino M, Altus P, Messina J, Wallach P M
Department of Internal Medicine, University of South Florida, Tampa.
South Med J. 1994 Sep;87(9):921-3. doi: 10.1097/00007611-199409000-00012.
Cases in which fibrotic variants of Hodgkin's disease have been confused with sclerosing mediastinitis have rarely been reported. Sclerosing mediastinitis typically involves the superior/middle mediastinum and, in the United States, is most commonly due to histoplasmosis. We describe the case of a patient who came to us with fevers, a mixed anemia, and a posterior mediastinal mass that on pathologic examination appeared to be due to idiopathic sclerosing mediastinitis. Only inclusion of a biopsy specimen from a local celiac node, after a new porta hepatis mass was found, revealed the correct diagnosis of Hodgkin's disease of the nodular sclerosing type. With the correct diagnosis, early intervention and appropriate therapy resulted in clinical cure.
霍奇金病的纤维化变体被误诊为硬化性纵隔炎的病例鲜有报道。硬化性纵隔炎通常累及上/中纵隔，在美国，其最常见的病因是组织胞浆菌病。我们描述了一例患者，该患者因发热、混合性贫血以及后纵隔肿块前来就诊，病理检查显示该肿块似乎是特发性硬化性纵隔炎所致。在发现肝门新肿块后，仅对局部腹腔淋巴结进行活检，才明确诊断为结节硬化型霍奇金病。明确诊断后，早期干预和适当治疗使患者实现了临床治愈。
